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Penile Cancer

A white or red spot is often the first sign of penile cancer.
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Penile cancer, also called penis cancer, is rare. Its symptoms could also be symptoms of other conditions that are not cancer.

Still, you should be aware of changes on and around your penis and report them to your doctor. If you do have cancer, detecting it early gives your doctor a better chance to treat it successfully.

Symptoms of penile cancer

Symptoms of penile cancer include these changes to the tip, foreskin, or shaft of your penis:

  • White or red spot
  • Small, hard lumps
  • A sore that bleeds
  • Fluid or blood under the foreskin

Learn more about causes and treatments

In most cases, penile cancer starts in the foreskin or on the head of the penis. Other names include:

  • Bowen disease, when it starts on the shaft or other part of the genitals
  • Erythroplasia of Queyrat, when it starts on the head of the penis
  • Paget disease of the penis, or adenocarcinoma, when it starts in the sweat glands in the skin of the penis

A risk factor is anything that increases your chances of getting a disease.

HPV, or human papillomavirus, is a common virus you can get through sexual contact or other kinds of skin-to-skin contact. HPV infections can be treated, but if the infections return over and over, your risk increases for getting penile cancer.

Other risk factors include:

  • Not being circumcised
  • Being 55 or older
  • Smoking
  • Having AIDS

If the cancer is found early and the tumor is small, the tumor can be removed without removing any part of the penis. More advanced tumors may require removing parts of the penis.

In some cases, the entire penis is removed, and the scrotum and testicles may also be removed, depending on how much the cancer has spread. In a procedure called perineal urethrostomy, a new opening is created to control urination without a penis.

For penile cancer that has spread to the lymph nodes, surgery may extend to other parts of the groin.

UI Health Care has experts who focus only on cancers of the urinary system

Our experts focus on every aspect of penile cancer, including what your life will be like after your treatment.

Our doctors also are top researchers who are finding new treatments and therapies to help get you back to living your life. We are always searching for ways to make the best cancer treatments even better.

We participate in clinical trials of the latest breakthroughs in cancer treatment. This can give you the chance to have your cancer treated with a promising new therapy that is not yet available on the market.

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Locations and Offices

Cancer Center - Clinic D (3 PFP)
31500 Pomerantz Family Pavilion (PFP)
Level 3, Elevator M
1-319-356-4200
Clinic
Clinic D wayfinding and directional image
In Clinical Cancer Center
200 Hawkins Drive, Iowa City, IA 52242
Cancer Center - Infusion Suite (2 PFP)
21602 Pomerantz Family Pavilion (PFP)
Elevator M, Level 2
1-319-356-4200
Clinic
Interior image of the Clinical Cancer Center at UI Hospitals & Clinics
In Clinical Cancer Center
200 Hawkins Drive, Iowa City, IA 52242
Cancer Center - Infusion Suite (4 PFP)
Pomerantz Family Pavilion (PFP)
Elevator L, Level 4
1-319-356-4200
Clinic
Clinical Cancer Center
In Clinical Cancer Center
200 Hawkins Drive, Iowa City, IA 52242
Cancer Centralized Intake
Pomerantz Family Pavilion (PFP)
Level 1, Elevator L
1-319-356-4200
Clinic
Entry space for the Cancer Center's Intake center
In Clinical Cancer Center
200 Hawkins Drive, Iowa City, IA 52242
Radiation Therapy (LL PFP)
01505 Pomerantz Family Pavilion (PFP)
Elevator M, Lower Level
1-319-356-4200
Clinic
Radiation Therapy location photo
In Medical Center University
200 Hawkins Drive, Iowa City, IA 52242
Radiation Therapy (LL PFP)
01505 Pomerantz Family Pavilion (PFP)
Elevator M, Lower Level
1-319-356-4200
Clinic
Radiation Therapy location photo
In Medical Center University
200 Hawkins Drive, Iowa City, IA 52242
Cancer Clinic, Ankeny, Magazine Road
1-515-282-2921
Clinic
Ankeny, Magazine Road, exterior
In Ankeny, Magazine Road
1950 SW Magazine Road, Ankeny, IA 50023
Cancer Clinic, Des Moines, E. Court Ave
Suite 200
1-515-282-2921
Clinic
Mission Cancer + Blood Des Moines Court Avenue exterior.
In Des Moines, E. Court Ave
110 E. Court Avenue, Des Moines, IA 50309
Cancer Clinic, Des Moines, Laurel Street
1-515-282-2921
Clinic
Des Moines, Laurel Street, exterior.
In Des Moines, Laurel Street
411 Laurel St. Suite A300, Des Moines, IA 50314
Cancer Clinic, Waukee, SE Encompass Drive
1-515-282-2921
Clinic
Mission Cancer + Blood - Waukee, part of UI Health Care, exterior.
In Waukee, SE Encompass Drive
2565 SE Encompass Drive, Waukee, IA 50263
Radiation Oncology, Bettendorf, Kimberly Road
Suite 200
1-563-441-1998
Clinic
Quad Cities Cancer Services building in Bettendorf, Iowa
In Bettendorf, Kimberly Road
1351 Kimberly Road, Bettendorf, IA 52722
Hematology Oncology, Bettendorf, Kimberly Road
Suite 100
1-563-355-7733
Clinic
Quad Cities Cancer Services building in Bettendorf, Iowa
In Bettendorf, Kimberly Road
1351 Kimberly Road, Bettendorf, IA 52722
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Group therapy for cancer patients

We offer group therapy for men and women of all ages who have a cancer diagnosis. The therapy sessions provide a safe environment for supportive interactions, education, and sharing of experiences. The groups practice mindfulness, acceptance, and self-compassion. Wherever you are in your cancer journey—recently diagnosed, in active treatment, or finished with therapy—please join us.

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