Breast Cancer
Breast cancer occurs when cells in the breast grow out of control. There are many different types of breast cancer.
Most breast cancers begin in the ducts of lobules but can spread outside the breast through blood vessels and lymph nodes.
If found and treated early through screening, your chances of recovery are very good.
Dedicated breast cancer care team
At University of Iowa Health Care Holden Comprehensive Cancer Center, every breast cancer patient is treated by our team of breast cancer specialists who are dedicated to only treating breast cancer. They understand every aspect of the disease, and they know about the most recent treatment options — from chemotherapy to radiation therapy to surgery.
Our cancer treatment experts are also researchers who are developing and delivering cutting-edge treatments that improve quality of life and boost survival rates. These treatments include clinical trials, which give patients access to the most advanced treatment options and promising treatments that can increase your chances for recovery.
Breast cancer patients are treated in our breast health center, a dedicated space breast health across the spectrum, from screening to diagnosis and treatment of cancer. Breast surgeons, medical oncologists, radiologists and genetic counselors work together and see patients in one, convenient space.
Risk factors for breast cancer
The cause of breast cancer is not known, but some things are known to increase your chances of getting breast cancer.
Some risk factors like family history, race and age are non-modifiable factors you cannot change. Other risk factors, like being obese and drinking alcohol and other lifestyle factors, can be changed to help prevent cancer.
Non-modifiable risk factors include:
- Family history: If you have an immediate family member (mother, daughter, or sister) who has been diagnosed with breast cancer, your risk of getting breast cancer is higher than normal.
- Genetics: People who have inherited certain mutated genes from either of their parents can have a higher risk of getting women breast cancer. The BRCA1 and BRCA2 genes are the most common inherited genes to cause breast cancer.
- Sex: Some men get breast cancer, but women are far more likely to get breast cancer than men.
- Having dense breasts: Dense breast tissue can make it harder to find tumors on a regular screening mammogram. Women with dense breast tissue are also at higher risk of developing breast cancer.
- Age: After age 50, your risk of breast cancer increases.
- Personal history: If you’ve already had breast cancer, you have a higher risk of getting it again.
Modifiable risk factors:
- Being overweight or obese: Women with obesity after menopause have a higher risk of developing breast cancer than those at a healthy weight.
- Drinking alcohol: Alcohol use is linked to an increased risk of breast cancer
- Not getting enough exercise: Regular physical activity reduces in breast cancer risk.
- Not having children: Women who have not had children or had their first child after age 30 have a slightly higher risk of breast cancer
Signs and symptoms of breast cancer
Breast cancer is easier to treat if caught at an early stage, which is why it is important to stay aware of your breast health and to look for the signs of breast cancer. These include:
- Swelling in the breast
- Swelling in nearby areas, like your collar bone or under your arm
- Changes to breast skin, including irritation, redness, or a scaly appearance
- A nipple that turns inward
- Discharges from the nipple other than breast milk
If you have any of these symptoms, that doesn’t mean you have breast cancer. But you should discuss any changes in your breasts with your provider as soon as you can.
How breast cancer is diagnosed
Not all breast cancers have symptoms that you’ll notice. Screening tests are the most effective way to find breast cancer early, before the tumor has grown and spread.
Early detection can prevent death from breast cancer, because smaller tumors that are in the early stage of development are easier to treat successfully than tumors that have had time to grow and spread.
A screening is a test that looks for a disease when you have no symptoms. Women should have screening tests for breast cancer regularly. You should talk to your provider to learn how often to have those screenings.
The most common screening test is a mammogram, which is an X-ray of the breast that is used to find signs of cancer. UI Health Care uses the latest technology and techniques like digital breast tomosynthesis or 3D mammography.
If breast cancer is suspected, your care team will perform additional screening or a biopsy to confirm the tumor is cancerous.
Every cancer diagnosis is unique.
That’s why getting a second opinion matters. Our cancer experts can confirm your diagnosis and help you understand all your treatment options.
Treatments for breast cancer
Your age, menopausal status, stage and the type of breast cancer you have will determine how your breast cancer is treated. Most patients will receive a combination of treatments including breast cancer surgery, radiation, chemotherapy and clinical trials.
At Holden, your care team of breast cancer specialists consists of experts from different fields of medicine who only treat breast cancer patients. These specialists work together as a group to choose the best treatment options for you and your cancer.
Your team includes radiologists, medical oncologists, breast surgical oncologists, radiation oncologists, plastic surgeons, genetic counselors, pathologists, pharmacists, nurses, and laboratory-based scientists.
Together they will create a personalized treatment plan that may include a combination of surgery, chemotherapy, radiation, immunotherapy, or a clinical trial.
Comprehensive breast cancer care
In addition to your cancer care, Holden offers additional support for breast cancer patients through several initiatives, including:
- High-risk breast cancer clinic: A dedicated clinic for the evaluation, risk management and screening for women with a higher risk of breast cancer due to family history, genetic mutations, abnormal biopsies in the breast or extremely dense breasts.
- Genetic counseling: Our genetic counselors analyze your family history to calculate your risk for having a genetic mutation and will counsel you on which genetic test, if any, to undergo.
- Nurse navigators: Your breast cancer journey is handled by a nurse navigator who guides you through each step of your treatment plan through survivorship.
- Breast cancer survivorship clinic: After you’ve completed your treatment for breast cancer, you will be followed up in a survivorship clinic to help manage long term side effects and screen for recurrence.
- Lymphedema therapy: Lymphedema is a common side effect following cancer treatment. We offer a full spectrum of nonsurgical care options for treating lymphedema.
Breast cancer treatments
Breast cancer types
- Invasive ductal carcinoma
- Invasive lobular carcinoma
- Inflammatory breast cancer
- Paget's disease of the breast
- Ductal carcinoma in situ (DCIS)
- Estrogen receptor (ER)-positive breast cancer
- Progesterone receptor (PR)-positive breast cancer
- Human epidermal growth factor receptor 2 (HER2)-positive breast cancer
- Triple-negative breast cancer
Our Care Team
- Cancer
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- Radiology
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- Radiology
- Cancer
- Radiology
- Cancer
- Endocrinology
- Surgery
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- Genetics
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Locations and Offices
Patient Stories
Support Groups
Caring for a loved one with cancer presents a unique set of challenges.
Family and friends who are taking care of a cancer patient are invited to attend therapy group for caregivers.
In these groups, caregivers will offer support, exchange ideas, and learn strategies to cope with the stress that comes with caring for a cancer patient.
We offer group therapy for men and women of all ages who have a cancer diagnosis. The therapy sessions provide a safe environment for supportive interactions, education, and sharing of experiences. The groups practice mindfulness, acceptance, and self-compassion. Wherever you are in your cancer journey—recently diagnosed, in active treatment, or finished with therapy—please join us.
Awards and Recognition
An emerging body of evidence suggests that treatment at a comprehensive cancer center may offer patients better chances for long-term survival.
Each breast center must undergo a rigorous evaluation and review of its performance and meet or exceed nationally recognized quality performance measures for breast cancer treatment.