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You deserve a second opinion on your cancer diagnosis. We make it easy for you to get one.

No cancer is routine. If you’ve been diagnosed with cancer, you want to be sure your diagnosis is accurate and that you have the most up-to-date treatment plan.

Before you begin your cancer treatment, you owe it to yourself and your loved ones to get a second opinion to be sure you get the personalized care your diagnosis requires.

Holden Comprehensive Cancer Center is ready to quickly provide you with an expert second opinion to ensure you get the right care for your unique cancer. It’s as easy as making an appointment.

Experts in every type of cancer

Holden’s teams of cancer specialists are ready to provide you with a diagnosis and treatment plan personalized for your unique case of cancer. Every Holden oncologist specializes in a specific type of cancer.

While many hospitals can provide general cancer care, only Holden has medical and surgical oncologists working with cancer researchers who examine your cancer from the inside out, at the molecular level, to identify the unique makeup of the cells that caused your tumor.

That depth of knowledge gives us the ability to diagnose your cancer and recommend the most advanced treatment — not to fight just any cancer, but to fight your unique case of cancer.

Many patients who come to Holden for a second opinion learn that their doctor’s original diagnosis is accurate and their treatment plan is the one our oncologists recommend. They return home knowing that their care has been reviewed and endorsed by our world-class experts in their type of cancer.

HCCC nurse practitioner meets with patient

Your diagnosis matters

Studies have shown that NCI-designated comprehensive cancer centers have patient survival rates up to 25 percent higher than other centers.

Get a second opinion

World-class cancer diagnosis close to home

Holden is the only cancer center in Iowa to be designated by the National Cancer Institute as a comprehensive cancer center. There are less than 60 NCI-designated cancer centers in the United States.

Studies have shown that NCI-designated comprehensive cancer centers have patient survival rates up to 25 percent higher than other centers.

That’s because comprehensive cancer centers have the experts to provide the best patient care needed to support research into the diagnosis, treatment, and prevention of every type of cancer.

When you need a second opinion for your cancer diagnosis, all of that advanced world-class expertise is nearby, in Iowa, and just one phone call away.

More cancer clinical trials than any center in Iowa

Holden offers more clinical trials of promising new cancer therapies than any other center in Iowa. And we’re the only center in Iowa that offers phase 1 clinical trials for cancer, which offer new hope to patients who have no other options for their cancer treatment.

When you come to Holden for your second opinion, our cancer experts will be ready with firsthand knowledge of what groundbreaking treatments are available for your unique cancer diagnosis.

Your appointment will give you the peace of mind of knowing that you’re taking advantage of every option you have to get the best cancer care available, so you can make the most informed choice when you decide how to proceed with your care.

Second opinion
Be sure you are receiving the right diagnosis for your cancer treatment.
Schedule appointment
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  • Your Visit to Holden
    • Before your visit
      • Why Choose Holden
      • Preparing for your first visit
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Locations and Offices

Breast Health Center (4 PFP)
41569 Pomerantz Family Pavilion (PFP)
Elevator M, Level 4
1-319-356-4200
Clinic
Exterior photo of the holden comprehensive cancer center at the university campus
In Clinical Cancer Center
200 Hawkins Drive, Iowa City, IA 52242
Cancer Center - Clinic B (1 PFP)
Pomerantz Family Pavilion (PFP)
Level 1, Elevator M
1-319-356-4200
Clinic
Exterior photo of the holden comprehensive cancer center at the university campus
In Clinical Cancer Center
200 Hawkins Drive, Iowa City, IA 52242
Cancer Center - Clinic C (LL PFP)
01271 Pomerantz Family Pavilion (PFP)
Lower Level, Elevator L
1-319-356-4200
Clinic
Interior image of Ortho South Clinic at UI Hospitals & Clinics
In Clinical Cancer Center
200 Hawkins Drive, Iowa City, IA 52242
Cancer Center - Clinic D (3 PFP)
31500 Pomerantz Family Pavilion (PFP)
Level 3, Elevator M
1-319-356-4200
Clinic
Clinic D wayfinding and directional image
In Clinical Cancer Center
200 Hawkins Drive, Iowa City, IA 52242
Cancer Center - Infusion Suite (2 PFP)
21602 Pomerantz Family Pavilion (PFP)
Elevator M, Level 2
1-319-356-4200
Clinic
Interior image of the Clinical Cancer Center at UI Hospitals & Clinics
In Clinical Cancer Center
200 Hawkins Drive, Iowa City, IA 52242
Cancer Center - Infusion Suite (4 PFP)
Pomerantz Family Pavilion (PFP)
Elevator L, Level 4
1-319-356-4200
Clinic
Clinical Cancer Center
In Clinical Cancer Center
200 Hawkins Drive, Iowa City, IA 52242
Otolaryngology Clinic (2 PFP)
21291 Pomerantz Family Pavilion (PFP)
Level 2, Elevator L
1-319-356-2201
Clinic
Otolaryngology Clinic at UI Hospitals & Clinics
In Medical Center University
200 Hawkins Drive, Iowa City, IA 52242
Radiation Therapy (LL PFP)
01505 Pomerantz Family Pavilion (PFP)
Elevator M, Lower Level
1-319-356-4200
Clinic
Exterior image of UI Hospitals & Clinics
In Medical Center University
200 Hawkins Drive, Iowa City, IA 52242
Cancer Centralized Intake
Pomerantz Family Pavilion (PFP)
Level 1, Elevator L
1-319-356-4200
Clinic
Entry space for the Cancer Center's Intake center
In Clinical Cancer Center
200 Hawkins Drive, Iowa City, IA 52242
Radiation Oncology, Bettendorf, Kimberly Road
Suite 200
1-563-441-1998
Clinic
Quad Cities Cancer Services building in Bettendorf, Iowa
In Bettendorf, Kimberly Road
1351 Kimberly Road, Bettendorf, IA 52722
Hematology Oncology, Bettendorf, Kimberly Road
Suite 100
1-563-355-7733
Clinic
Quad Cities Cancer Services building in Bettendorf, Iowa
In Bettendorf, Kimberly Road
1351 Kimberly Road, Bettendorf, IA 52722
Clinical Trials currently in progress
Browse all clinical trials in progress

Patient Stories

Robotic surgery leads to lung cancer cure
November 20, 2025
Five years after a screening test found early-stage lung cancer, and a robotic procedure removed the tumor, a former smoker remains free from cancer.
Sharon Chamberlin
Iowa mom learns of cancer diagnosis after giving birth
May 22, 2025
I had no symptoms or any idea I was going to be told I had cancer.
Danika image
Browse more patient stories

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Educational Resources

What to expect during cancer treatment
Dry mouth during cancer treatment
Sore mouth during cancer treatment
Nausea and vomiting during cancer treatment
Taste changes during cancer treatment
Difficulty swallowing and chewing during cancer treatment
Constipation during cancer treatment
Gas and bloating during cancer treatment
Diarrhea during cancer treatment
Loss of appetite or weight during cancer treatment
Food safety during cancer treatment
Thoughts for the caregiver/cook during cancer treatment
Tips for better sleep for cancer patients
The complete blood count: A guide for patients with cancer

Support Groups

American Cancer Society - Look Good...Feel Better Program

Service provided by the Fourth Floor Salon cosmetologists.

Learn more about the Look Good...Feel Better® Program.

American Cancer Society Resource Center - Burlington
Blood and Marrow Transplant Caregiver Support Group - Des Moines

For caregivers, this group will be a blend of open discussion, as well as educational information to help with practical advice and guidance from both health-care professionals and other caregivers themselves.

Blood Cancer Family Support Group - Des Moines

For adult patients with leukemia, lymphoma, Hodgkin's disease, myeloma, or myelodysplastic syndromes and their family and friends

Blood Cancer Support Group - Iowa City

This gathering offers support and open discussion around a diagnosis of leukemia, Hodgkin lymphoma, non-Hodgkin lymphoma or multiple myeloma for patients, family members, friends and survivors.

Affiliated with Leukemia and Lymphoma Society

Cancer Caregiver Support Group

Caring for a loved one with cancer presents a unique set of challenges. 

Family and friends who are taking care of a cancer patient are invited to attend therapy group for caregivers.

In these groups, caregivers will offer support, exchange ideas, and learn strategies to cope with the stress that comes with caring for a cancer patient.

Cancer Patient Therapy
Cleaning for a Reason - Keokuk

Provides free house cleaning once per month for four months during the time the woman is in treatment, and helps women who are going through cancer treatment

Community Hospital Outreach Cancer Support Group - Fort Madison
Group therapy for cancer patients

We offer group therapy for men and women of all ages who have a cancer diagnosis. The therapy sessions provide a safe environment for supportive interactions, education, and sharing of experiences. The groups practice mindfulness, acceptance, and self-compassion. Wherever you are in your cancer journey—recently diagnosed, in active treatment, or finished with therapy—please join us.

Henry County Outreach Support Group
Keokuk Outreach Cancer Support Group
Leukemia and Lymphoma Society Telephone Support Group

Visit their website.

Multiple Myeloma Support Group of Eastern Iowa

Offered by UI Health Care's Blood and Marrrow Transplant Program for patients and caregivers.

What's on Your Mind? - Des Moines

A group or individual counseling program for people with cancer and/or their families. Patients and family members are welcome to come to group counseling or may set up individual appointments.

Call for more information on meeting dates and locations.

Yoga Support Group for Cancer Survivors - Iowa City

This group is open to any cancer survivor in the community. Participants must submit a signed medical waiver prior to starting. Waivers can be faxed or emailed. Please wear comfortable clothes and bring your own yoga mat.

Meetings are held over zoom.

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Awards and Recognition

U.S. News & World Report - Cancer
In 2025-26 our Cancer program was ranked 42 in the nation by U.S. News & World Report.
Learn more
Iowa's only NCI-designated comprehensive cancer center
Holden Comprehensive Cancer Center is the only NCI-designated comprehensive cancer center in Iowa. This designation recognizes our ability to offer Iowans more cancer treatment options than most U.S. cancer centers, including a vast array of clinical trials of some of the newest therapies.

An emerging body of evidence suggests that treatment at a comprehensive cancer center may offer patients better chances for long-term survival.
Learn more
The American College of Surgeons Commission on Cancer (CoC)
Holden Comprehensive Cancer Center is one of the nation’s longest accredited cancer centers from the Commission on Cancer (CoC), a quality program of the American College of Surgeons (ACS).

To achieve CoC accreditation, cancer centers are regularly reviewed to ensure they meet standards that evaluate the services offered by the program.

As a CoC-accredited cancer center, Holden applies a multidisciplinary approach and treats cancer as a complex group of diseases that requires consultation and collaboration among surgeons, medical and radiation oncologists, diagnostic radiologists, pathologists, and other health care professionals that specialize in cancer care. Patients benefit from having access to clinical trials, screening and prevention events, palliative care, genetic counseling, rehabilitation, oncology nutrition, and survivorship services.
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