Estrogen

What is estrogen?

It is a hormone secreted by the ovarian follicles. It causes:

• An increase in cervical mucus
• Thickening of vaginal wall
• Growth of the endometrium (lining of the uterus)

Estrogen replacement therapy (Estrace®) can be used to mimic a natural menstrual cycle. It is used when the ovaries are not working or have been removed. Menstrual flow may start 48 to 72 hours after stopping estrogen.

What risks are of estrogen therapy?

It should not be used if you have:

• Known or suspected breast cancer
• Known or suspected estrogen-dependent tumor
• An active blood clotting disorder

What are the side effects?

The most common complaint is nausea. Other side effects are:

• Changes in menstrual flow
  • You may have breakthrough bleeding with prolonged doses.
• Breast changes, such as tenderness, enlargement, or secretion
• Headache
• Blood clotting problems
• High blood pressure
• Fluid retention
• Mood swings