Also know as Otezla, apremilast treats psoriasis and psoriatic arthritis. It regulates inflammation in the body. It blocks an enzyme known as phosphodiesterase 4 (PDE4), which often causes more inflammation. It is a pill that you will take two times a day.
Side effects of apremilast
Nausea (feeling like you need to vomit)
These often get better or go away during the first 4 to 6 weeks of taking the medicine.
Other side effects of apremilast
Respiratory infections (colds)
Low mood (depression)
Tell your doctor if you have a history of depression.
Signs of depression
Changes in sleep and appetite
Loss of interest in activities that you used to enjoy
Feelings of worthlessness or guilt
Changes in mood
Thoughts of hurting yourself or others
Stop the medicine and call your doctor if you have any of the above symptoms.
How to take apremilast
To lower the risk of nausea and diarrhea, start the medicine with a starter pack. You will slowly take a higher dose over many days until you reach a goal dose of 30 mg 2 times a day. Tell your doctor if you have a history of kidney disease, this can change your recommended dose.