Sioux City, Pierce Street

2501 Pierce St., Sioux City, IA 51104

Sioux City, Pierce Street clinic on Tuesday, May 20, 2025.

Location hours

  • Monday – Friday: 8:00am – 5:00pm
Clinic and amenities hours may vary.
See all clinic and amenities at this location.
1-712-294-5000

Driving directions and parking

2501 Pierce St., Sioux City, IA 51104

42.51618, -96.40519

Turn-by-turn directions

Providing quality, compassionate, and comprehensive patient care

In 2023, University of Iowa Health Care assumed operations of the Family Medicine Center, and its family medicine residency program—the only such training program in western Iowa.

The Family Medicine Center was established in 1975 in collaboration with MercyOne Siouxland Medical Center and Unity Point–St. Luke’s Hospital Sioux City.

For nearly 50 years, the health and wellness of our patients has been our primary focus.  We see patients for pregnancy care, baby wellness, vaccinations, school and athletic physicals, acute care visits, annual physicals, regular check-ups, mental health, and more. We provide extensive on-site laboratory and radiology services. Our pharmacists are available for medication consultation and medication management services.

Contact

Phone: 1-712-294-5000
Fax: 1-712-294-5092

Schedule Online with Family Medicine

Not seeing appointment options that work for you?

If you don't see the appointment type or availability you are looking for, we're here to help. For medical emergencies, please call 911.

Call for an Appointment
Call our integrated call center to discuss available appointments and determine the right next steps.
Submit an appointment request form
You can request care via our online web form, and a scheduler will contact you to discuss what available options are right for you.
Schedule through MyChart
For return patients, MyChart is the fastest, easiest, and most accessible way to schedule your care.

Services available

Family Medicine
Family Medicine Psychiatry
Lung cancer screening
Obstetrics and Gynecology (OBGYN)
Pathology
Phlebotomy Services
Pregnancy Care
Radiology
Phlebotomy Services
Radiology

At this Location

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Need help selecting a provider?

When you call 1-712-294-5000 or 1-800-777-8442 we'll help you find a provider who meets your needs.
Call 1-888-573-5437 Call 1-712-294-5000

Patient Stories

Urbandale 7th grader pays it forward after battling brain cancer
November 10, 2025
Blake Bonta came to Stead Family Children’s Hospital after his local hospital discovered a mass in the back of his brain
Kid Captain Blake Bonta
Illinois parents find care for son’s rare spinal condition at Stead Family Children’s Hospital
October 20, 2025
After a 13-hour surgery last Halloween, Luke Johnston connected with his Iowa care team including the hospital facility dog, Corrin
Kid Captain Luke Johnston
Browse more patient stories

Related News

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February 11, 2026
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February 26, 2025
CertaScan technology, meant to enhance patient safety for newborns, is launching at University of Iowa Health Care’s downtown campus.
CertaScan technology

Awards and Recognition

U.S. News & World Report - Maternity Care
University of Iowa Health Care has been named one of the nation’s top hospitals for maternity care in 2026 by U.S. News & World Report.
Learn more
Comprehensive Radiopharmaceutical Therapy Center Designation
Comprehensive Radiopharmaceutical Therapy Center Designation
University of Iowa Health Care University Campus has achieved the Comprehensive Radiopharmaceutical Therapy Center designation. We are one of 46 centers that have achieved this.
Learn more
U.S. News & World Report - Maternity Care
University of Iowa Health Care has been named one of the nation’s top hospitals for maternity care in 2026 by U.S. News & World Report.
Learn more