Sioux City, Pierce Street

2501 Pierce St., Sioux City, IA 51104

Sioux City, Pierce Street clinic on Tuesday, May 20, 2025.

Location hours

  • Monday – Friday: 8:00am – 5:00pm
Clinic and amenities hours may vary.
See all clinic and amenities at this location.
1-712-294-5000

About this location

Pediatric care available

Driving directions and parking

2501 Pierce St., Sioux City, IA 51104

42.51618, -96.40519

Turn-by-turn directions

Providing quality, compassionate, and comprehensive patient care

In 2023, University of Iowa Health Care assumed operations of the Family Medicine Center, and its family medicine residency program—the only such training program in western Iowa.

The Family Medicine Center was established in 1975 in collaboration with MercyOne Siouxland Medical Center and Unity Point–St. Luke’s Hospital Sioux City.

For nearly 50 years, the health and wellness of our patients has been our primary focus.  We see patients for pregnancy care, baby wellness, vaccinations, school and athletic physicals, acute care visits, annual physicals, regular check-ups, mental health, and more. We provide extensive on-site laboratory and radiology services. Our pharmacists are available for medication consultation and medication management services.

Contact

Phone: 1-712-294-5000
Fax: 1-712-294-5092

Schedule Online with Family Medicine

Not seeing appointment options that work for you?

If you don't see the appointment type or availability you are looking for, we're here to help. For medical emergencies, please call 911.

Call for an Appointment
Call our integrated call center to discuss available appointments and determine the right next steps.
Submit an appointment request form
You can request care via our online web form, and a scheduler will contact you to discuss what available options are right for you.
Schedule through MyChart
For return patients, MyChart is the fastest, easiest, and most accessible way to schedule your care.

Services available

Family Medicine
Family Medicine Psychiatry
Lung cancer screening
Obstetrics and Gynecology (OBGYN)
Pathology
Phlebotomy Services
Pregnancy Care
Radiology
Phlebotomy Services
Radiology

At this Location

Select office type

Need help selecting a provider?

When you call 1-712-294-5000 or 1-800-777-8442 we'll help you find a provider who meets your needs.
Call 1-800-777-8442 Call 1-712-294-5000

Patient Stories

UPDATE: Quad Cities physicians helping family expand with coordinated, convenient care
February 24, 2026
Ear infection? Congenital heart condition? Pregnancy? No matter the situation, the Hoak family starts with UI Health Care’s family medicine team.&nbsp...
Hoak family of five
Iowa boy born at 21 weeks is now the world's most premature baby
July 23, 2025
Born at 133 days premature, Nash Keen is the new Guinness World Records title holder for the most premature baby
Nash Keen, world's most premature baby
Browse more patient stories

Related News

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One nurse’s quick action saves two lives
October 19, 2026
Knowing seconds can mean survival, early action to alert the obstetrics, nursing, and anesthesia teams about a patient saved two lives when an emergen...
Ashley Patterson, BSN, RN receiving her Daisy Award surrounded by teammates
UI Health Care family medicine clinic now open in Tiffin
October 5, 2026
New clinic expands access to primary care in the growing community
Rbbon cutting and opening event at the UI Health Care Tiffin, North Kimberlite Street Family Medicine clinic on Tuesday, Sept. 29, 2026.

Educational Resources

Cryotherapy
Perinatal mood and anxiety disorders (PMADs)
Why do I need a colposcopy?
Nitrous Oxide During Childbirth
Percutaneous Nephrostomy Tube: Flushing the Tube
Percutaneous Nephrostomy Tube: Leakage
Percutaneous Nephrostomy Tube: Displacement, Suture, and Pulling
Percutaneous Nephrostomy Tube: Changing the Dressing and Showering
Percutaneous Nephrostomy Tube: Wearing, Emptying, and Changing the Urine Collection Bag
Percutaneous Nephrostomy Tube
Hysteroscopic Polypectomy and Dilation and Curettage (D&C)
IVF pregnancy guidelines
In vitro fertilization (IVF) treatment cycle start instructions
Preconception nutrition
Oral contraceptive pills (OCP) during IVF cycle
Progesterone supplementation
Ovulation predictor kits (OPK)
Eating concerns in early pregnancy
Clomiphene citrate therapy
Vaginal dilator
Methotrexate for ectopic pregnancy
Planned induction of labor
Treating vaginal intraepithelial neoplasia (VAIN) or condyloma lesions
Treating vulvar intraepithelial neoplasia (VIN) or condyloma lesions
Clean intermittent self-catheterization
Pessary for treating prolapse
Stress urinary incontinence and urethral bulking injections
Urethral (indwelling) catheter care
Amniocentesis/chorionic villus sampling
Hormonal (Progestin) Intrauterine Devices
Progestin only birth control pills
Etonogestrel Implant (Nexplanon®) Removal
Etonogestrel (Nexplanon®) Implant
Pre-operative instructions for women having a planned cesarean (C-section)
Emergency contraception (EC)
Combination Oral Contraceptive (COC) Pills
Breastfeeding and Supplementation Guide
Lupron Depot
Sharing the news and getting ready for birth after unexpected news
Care and support services after unexpected news
Journey to your baby after unexpected news
Insulin Use During Pregnancy
Myelogram
Magnetic resonance imaging (MRI)
Computed tomography
Communicating during your doctor visit
Over-the-counter medications
What you need to know about an epidural
Acclimatization (adjusting to the temperature)
3 ways to protect yourself from cervical cancer
5 things you should know about prenatal care
Cold and flu medications pose risks for those with high blood pressure
Prevention and treatment of high blood pressure (hypertension)
Vulvar skin care guidelines
How to read your blood pressure

Awards and Recognition

U.S. News & World Report - Maternity Care
University of Iowa Health Care has been named one of the nation’s top hospitals for maternity care in 2026 by U.S. News & World Report.
Learn more
Comprehensive Radiopharmaceutical Therapy Center Designation
Comprehensive Radiopharmaceutical Therapy Center Designation
University of Iowa Health Care University Campus has achieved the Comprehensive Radiopharmaceutical Therapy Center designation. We are one of 46 centers that have achieved this.
Learn more
U.S. News & World Report - Maternity Care
University of Iowa Health Care has been named one of the nation’s top hospitals for maternity care in 2026 by U.S. News & World Report.
Learn more